New Research Sheds Light on Biological Causes of Long COVID Symptoms

Scientists say new research is providing clearer insight into the biological mechanisms that may underlie long COVID, a condition affecting millions of people worldwide following coronavirus infection.

Recent studies examining blood markers, immune responses, and tissue samples suggest that persistent inflammation, immune system dysregulation, and changes in blood clotting may contribute to long-term symptoms such as fatigue, breathlessness, and cognitive difficulties.

Researchers involved in the work report that some patients show signs of ongoing immune activation months after initial infection, even when no active virus is detected. Other findings point to damage in small blood vessels, which may help explain the wide range of symptoms reported by people with long COVID.

Scientists stress that the condition is complex and likely involves multiple biological pathways rather than a single cause. While the findings do not yet translate into specific treatments, researchers say they represent an important step toward understanding the condition and guiding future clinical studies.

Health experts say continued research will be essential to develop effective therapies and support strategies for those affected, particularly as long COVID remains a significant public health concern.

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